In St. Stamford Modern Cancer Hospital Guangzhou, how long is the duration of minimally invasive surgery and how long does the patients need to stay in hospital? A minimally invasive surgery may last for 40 minutes to one hour. If you just need to do a minimally invasive surgery, like our patient in domestic, they could be discharged after observing for 2 or 3 days. But for patients coming from abroad, maybe some of them will stay for a few more days.