Radiofrequency ablation, sometimes referred to as RFA, is a minimally invasive treatment for cancer. It is an image-guided technique that heats and destroys cancer cells. Under the guidance of image, RFA, a physical method to inactive and kill the tumor, is performed with minimally invasive paracentesis to introduce the heat generator into the tumor. Ablation is targeting and can affect the tumor strongly while no side effect happens to normal tissues around. The result of RFA is same as invasive surgery, so it is a special knife without operation—Ablation knife.