Stomach Cancer
Stomach cancer, also known asgastric cancer, is a malignant tumor that arises from the lining of the stomach. Most stomach cancers develop slowly over many years, often beginning as precancerous changes in the gastric mucosa before progressing into invasive cancer.
The stomach is a hollow muscular organ located in the upper abdomen that plays a critical role in digestion. Cancer can develop in any part of the stomach, but it most commonly affects thebody and antrum. In recent years, cancers near thegastro-esophageal junctionhave become more common.
Despite declining incidence globally, stomach cancer remains amajor cause of cancer-related mortality, especially in East Asia, including Japan, Korea, and China.
Types
Primary Liver Cancer
Cancer that starts in the liver.
Hepatocellular carcinoma (HCC)
Most common type (≈75–85%)
Originates from hepatocytes
Intrahepatic cholangiocarcinoma
Arises from bile ducts within the liver
More aggressive, poorer prognosis
Hepatoblastoma
Rare
Occurs mainly in children
Secondary (Metastatic) Liver Cancer
Cancer that spreads to the liver from other organs such as:
Colon
Lung
Breast
Pancreas
(Metastatic tumors are more common than primary liver cancer.)
Stages
Liver cancer staging considerstumor size, number, vascular invasion, liver function, and spread.
Early Stage
Small tumor(s)
Confined to the liver
Liver function relatively preserved
Potentially curable
Intermediate Stage
Multiple tumors
No distant spread
Limited treatment options
Advanced Stage
Invasion into blood vessels
Spread to lymph nodes or distant organs
Symptoms more severe
End Stage
Poor liver function
Extensive tumor burden
Palliative care focus
Risk Factors
ChronicHepatitis B or C infection
Liver cirrhosis (any cause)
Alcohol-related liver disease
Non-alcoholic fatty liver disease (NAFLD)
Diabetes and obesity
Exposure toaflatoxins(contaminated food)
Smoking
Family history of liver cancer
Symptoms
Early liver cancer is often asymptomatic.
As the disease progresses:
Right upper abdominal pain or discomfort
Unexplained weight loss
Loss of appetite
Fatigue and weakness
Abdominal swelling (ascites)
Jaundice (yellowing of skin and eyes)
Nausea or vomiting
Easy bruising or bleeding
Diagnosis
Diagnosis usually involves a combination of:
Blood Tests
Alpha-fetoprotein (AFP)
Liver function tests
Viral hepatitis screening
Imaging Studies
Ultrasound (screening tool)
CT scan
MRI (high sensitivity for liver lesions)
Biopsy
Confirms diagnosis when imaging is inconclusive
Sometimes avoided if imaging is characteristic
Facts (FAQ)
Q1: Can liver cancer be prevented?
Yes. Vaccination against Hepatitis B, early treatment of Hepatitis C, avoiding excessive alcohol, and maintaining a healthy weight significantly reduce risk.
Q2: Is liver cancer curable?
Early-stage liver cancer may be curable with surgery or transplantation. Advanced stages are usually not curable but treatable.
Q3: Who should be screened?
People with chronic hepatitis, cirrhosis, or long-term liver disease should undergo regular screening.
Q4: Does liver cancer grow fast?
Growth rate varies. Some tumors progress slowly, while others are aggressive.
Q5: Is liver cancer painful?
Pain usually occurs in later stages when the tumor enlarges or spreads.














































