Significance: Radiofrequency ablation significantly enhances cellular immune function in lung cancer patients, playing an important role in comprehensive treatment.

Effect of Radiofrequency Ablation on Immune Function in Liver Cancer Patients

Significance: Patients with primary liver cancer often present with immunosuppression. Radiofrequency ablation significantly enhances immune function, offering important therapeutic benefits.

Dr. Dai Wenyan

Head of Breast Specialty

Over 20 years of experience in oncology

Expert in breast cancer diagnosis and treatment

Research paper:

Comparative Analysis of Clinical Efficacy of Argon-Helium Cryoablation Combined with Chemotherapy versus Chemotherapy Alone in the Treatment of Advanced Triple-Negative Breast Cancer

Significance: Argon-helium cryoablation combined with chemotherapy achieves a synergistic effect (1+1>2) in the treatment of advanced triple-negative breast cancer, with progression-free survival superior to chemotherapy alone

Analysis of ¹²⁵I Seed Implantation for Retroperitoneal Lymph Node Metastases

Significance: ¹²⁵I seed implantation significantly alleviates pain and provides effective local tumor control in patients with retroperitoneal lymph node metastases

Dr. Huang Zuoping

International Oncology Specialist

M.D.

Over 30 years of clinical experience

Research paper:

The Complete Recanalization of PICC-related Venous Thrombosis in Cancer Patients: A Series of Case Reports

Significance: This provides a feasible and effective treatment option for cancer patients with PICC-related venous thrombosis.

Dr. Ma Xiaoying

Head of Gastrointestinal Oncology

Over 20 years of experience in oncology

Expert in Gastrointestinal Endoscopy

Research paper:

Clinical Observation of Argon-Helium Cryoablation Combined with FOLFIRI Regimen for Postoperative Liver Metastases from Colorectal Cancer

Significance: Argon-helium cryoablation combined with systemic FOLFIRI chemotherapy achieves superior efficacy in treating postoperative liver metastases from colorectal cancer compared with systemic chemotherapy alone.

Dr. Wang Ligen

Director, International Medical Technology Exchange Center

M.D.

Over 40 years of clinical and research experience in oncology

Research paper:

Californium-252 neutron brachytherapy combined with external pelvic radiotherapy plus concurrent chemotherapy for cervical cancer: a retrospective clinical study

Significance: Californium-252 neutron brachytherapy combined with external pelvic radiotherapy and concurrent cisplatin chemotherapy achieves rapid onset of action in cervical cancer patients, significantly improving local control and long-term survival with manageable toxicity.

Dr. Wang Baoli

International Oncology Specialist

Member of the Interventional Professional Committee, Guangzhou Medical Association

Over 20 years of experience in oncology

Research paper:

Treatment of mid-late stage NSCLC using sodium cantharidinate/vitamin B6/GP regimen in clinic

Significance: The combination of sodium cantharidinate/vitamin B6 with the GP regimen achieves a higher response rate and improved quality of life in patients with mid-late stage non-small cell lung cancer.

Leading Experts: Pioneers in Clinical Research

Paper Classification

Effect of Radiofrequency Ablation on Immune Function in Lung Cancer Patients

Abstract: Objective: To investigate the effect of radiofrequency ablation on immune function in lung cancer patients. Conclusion: Radiofrequency ablation significantly enhances immune function in lung cancer patients and plays an important role in comprehensive treatment.

Authors: Song Shijun, et al.

Source: *Journal of Clinical Psychosomatic Diseases*, Volume 22, Issue 3, May 2016

Clinical Study of Docetaxel Combined with Oxaliplatin versus Docetaxel Combined with Cisplatin in the Treatment of Advanced Non-Small Cell Lung Cancer

Abstract:Objective: To observe the short-term efficacy and toxicity of docetaxel combined with oxaliplatin versus docetaxel combined with cisplatin in the treatment of advanced non-small cell lung cancer.

Authors: He Jianyu, et al.

Source: Journal of Tongji University (Medical Edition), Issue 6, 2010, pp. 83–88

Clinical Observation and Nursing Care of Radioactive ¹²⁵I Seed Implantation in the Treatment of Advanced Lung Cancer

Abstract: To analyze the complications and nursing strategies of CT-guided ¹²⁵I seed implantation in the treatment of advanced lung cancer. Conclusion: Postoperative vital signs should be closely monitored, and timely measures should be taken to prevent and manage complications.

Authors: Wang Junlan, Xiao Juan, et al.

Source: Nursing Practice and Research, Volume 9, Issue 13 (First Half), 2012, pp. 85–86

Effect of Radiofrequency Ablation on Immune Function in Liver Cancer Patients

Abstract: Objective: To investigate the effect of radiofrequency ablation on immune function in liver cancer patients. Conclusion: Patients with primary liver cancer often present with immunosuppression, and radiofrequency ablation significantly improves immune function.

Authors: Song Shijun, et al.

Source: Journal of Clinical Psychosomatic Diseases, Volume 25, Issue 3, May 2019

Clinical Efficacy Evaluation of Hepatic Arterial Thermochemoembolization Combined with CT-Guided Radiofrequency Ablation for Liver Malignancies

Abstract: Objective: To evaluate the clinical efficacy of hepatic arterial thermochemoembolization combined with CT-guided radiofrequency ablation for liver malignancies. Conclusion: This combined treatment significantly improves immune function in patients.

Authors: Zhen Yanli, Ban Zhonghua, et al.

Source: Modern Medical Imaging, 2020, Vol. 29, No. 6

Evaluation of the Clinical Application Value of Palliative Treatment for Advanced Gastrointestinal Malignancies

Abstract: Objective: To investigate the clinical application value of palliative treatment for advanced gastrointestinal malignancies, providing reference for clinical practice. Conclusion: Brucea javanica oil emulsion injection combined with compound matrine injection demonstrates significant clinical efficacy in the treatment of advanced gastrointestinal malignancies, improving patients' quality of life and alleviating disease-related suffering.

Authors: Song Shijun, et al.

Source: China Practical Medicine, Volume 11, Issue 9, March 2016

Effects of Erufosine on Proliferation Inhibition in Gastric Cancer Cells and Bone Marrow Cells

Abstract: This study investigates the effects of the small molecule compound Erufosine on the proliferation of gastric cancer cells and normal bone marrow cells, as well as its impact on the expression of the signaling molecule Akt, and explores its mechanism of action in cancer cells.

Authors: He Jianyu, et al.

Source: China Oncology, Peking University Core Journal · CSCD, Issue 9, 2011, pp. 675–680

Value of Combined Detection of Pepsinogen and Its Ratio, Gastrin-17, and Helicobacter pylori IgG Antibody in Gastric Cancer Screening

Abstract: Objective: To evaluate the value of combined detection of pepsinogen, gastrin-17, and Helicobacter pylori antibody in gastric cancer screening. Conclusion: Combined detection of pepsinogen, gastrin-17, and Helicobacter pylori antibody can improve the detection rate of gastric cancer and holds significant clinical reference value.

Authors: He Jianyu, et al.

Source: Labeled Immunoassays and Clinical Medicine, Issue 9, 2020, pp. 1516–1519, 1533

Analysis of Short-term Efficacy and Safety of PD-1 Monoclonal Antibody Combined with Anlotinib, Paclitaxel, and Cisplatin in Advanced Esophageal Cancer

Abstract: Objective: To observe the short-term efficacy and safety of programmed death receptor-1 (PD-1) monoclonal antibody combined with anlotinib, paclitaxel, and cisplatin in the treatment of advanced esophageal cancer. Conclusion: PD-1 monoclonal antibody combined with anlotinib, paclitaxel, and cisplatin demonstrates favorable disease control in advanced esophageal cancer with manageable adverse reactions, providing a new treatment strategy for clinical practice.

Authors: Ma Xiaoying, Zhai Xueli, et al.

Source: Chinese Journal of Modern Drug Application, Issue 9, 2021, pp. 155–157

Observation on Short-term Efficacy of Anti-PD-1 Monoclonal Antibody Combined with Anlotinib in the Treatment of Advanced Esophageal Cancer

Abstract: Objective: To observe the short-term efficacy and safety of anti-programmed death receptor-1 (PD-1) monoclonal antibody combined with anlotinib in the treatment of advanced esophageal cancer. Conclusion: Anti-PD-1 monoclonal antibody combined with anlotinib demonstrates favorable disease control in advanced esophageal cancer with good tolerability, providing a new treatment strategy for clinical practice.

Authors: Ma Xiaoying

Source: China Practical Medicine, Issue 36, 2021, pp. 126–128

Expert Consensus on Ablation Therapy for Breast Cancer Patients Without Surgical Indications (2025 Edition)

Abstract: Ablation therapy is suitable for breast cancer patients who are unable or unwilling to undergo surgery, offering advantages such as minimal invasiveness and breast preservation. This consensus standardizes the operational procedures for ablation therapy.

Authors: Dai Wenyan, et al.

Source: Chinese Journal of Breast Disease (Electronic Edition), Volume 20, Issue 1, February 2026

Argon-Helium Cryoablation Combined with Systemic Therapy for Advanced Breast Cancer Invading the Skin with Ulceration and Bleeding

Abstract: Breast cancer ranks first in incidence among female malignancies, with low cure rates after metastasis. Treatment should primarily aim to alleviate symptoms, improve quality of life, and prolong survival. This study reports the efficacy of argon-helium cryoablation combined with systemic therapy in 51 patients with advanced large breast cancer invading the skin with ulceration and bleeding.

Authors: Dai Wenyan, Qin Yubing, Zhao Yifan

Source: Chinese Journal of Interventional Imaging and Therapy, Issue 11, 2022, pp. 729–731

Comparative Analysis of Clinical Efficacy of Argon-Helium Cryoablation Combined with Chemotherapy versus Chemotherapy Alone in the Treatment of Advanced Triple-Negative Breast Cancer

Abstract: Argon-helium cryoablation combined with chemotherapy achieves a synergistic effect (1+1>2) in the treatment of advanced triple-negative breast cancer, with progression-free survival superior to chemotherapy alone. This approach is safe, minimally invasive, and does not increase chemotherapy-related adverse reactions. It effectively alleviates symptoms, improves quality of life, and demonstrates significant short-term efficacy, representing a safe and effective combination treatment strategy.

Authors: Dai Wenyan, Pan Xin, et al.

Source: Jilin Medical Journal, Issue 10, 2019, pp. 2228–2231

Clinical Observation of Argon-Helium Cryoablation Combined with FOLFIRI Regimen for Postoperative Liver Metastases from Colorectal Cancer

Abstract: Objective: To observe the efficacy and safety of argon-helium cryoablation combined with FOLFIRI regimen in the treatment of postoperative liver metastases from colorectal cancer. Conclusion: Argon-helium cryoablation combined with systemic FOLFIRI chemotherapy demonstrates definitive efficacy in treating postoperative liver metastases from colorectal cancer, with superior outcomes compared to systemic chemotherapy alone.

Authors: Ma Xiaoying, et al.

Source: China Practical Medicine, Issue 28, 2016, pp. 66–67

Assessing the Safety and Efficacy of Fecal Microbiota Transplantation for Severe Chemotherapy-Induced Diarrhea in Colorectal Cancer Patients: A Single-Arm Clinical Trial

Abstract: Diarrhea is a significant complication in colorectal cancer (CRC) patients receiving cytotoxic chemotherapy, impacting their quality of life and treatment adherence. Objective: To evaluate the safety and efficacy of fecal microbiota transplantation (FMT) for severe chemotherapy-induced diarrhea (CID) in CRC patients.

Authors: Modern Cancer Hospital Guangzhou

Source: International Journal of Clinical Practice, Volume 2025, Article ID 8052716, 12 pages

Californium-252 (²⁵²Cf) neutron brachytherapy combined with external pelvic radiation for cervical cancer: a retrospective clinical study

Abstract: Cervical cancer is the sixth most common cancer among women in China. This study retrospectively analyzed the long-term efficacy and safety of ²⁵²Cf neutron brachytherapy combined with external beam radiotherapy and cisplatin chemotherapy in 150 patients with stage IB-IVB cervical cancer, evaluating survival outcomes and adverse reactions.

Authors: Wang Ligen, Huang Zuoping, et al.

Source: Chinese Journal of Cancer, Volume 35, Issue 04, 2017, pp. 35–43

Small cell carcinoma of the uterine cervix: a multi-institutional experience

Abstract: Small cell carcinoma of the uterine cervix is a rare malignancy characterized by high aggressiveness and poor prognosis. This retrospective study analyzed clinical data from 93 patients across three centers between 2001 and 2015, evaluating the impact of clinicopathological factors on disease-free survival (DFS) and overall survival (OS). Prognostic factors were analyzed using Kaplan-Meier and Cox regression methods.

Authors: Wang Ligen, et al.

Source: International Journal of Gynecological Cancer, Volume 30, Issue 2, February 2020, pp. 174–180; DOI: 10.1136/ijgc-2019-000612

Ovarian Cancer Transformation from Adenocarcinoma to Undifferentiated Small Cell Carcinoma: A Case Report

Abstract: Objective: To investigate the role of tumor stem cells in histological transformation of ovarian cancer and emphasize the importance of treatment evaluation through repeat biopsy during the course of therapy. Conclusion: Any histological changes observed in ovarian tumors originate from tumor stem cells, highlighting the critical need for repeated assessment via tumor biopsy throughout the treatment course of ovarian cancer.

Authors: Huang Zuoping, et al.

Source: Oncology Letters, 9(5), pp. 2230–2232

Radioactive ¹²⁵I Seed Inhibits the Cell Growth, Migration, and Invasion of Nasopharyngeal Carcinoma by Triggering DNA Damage and Inactivating VEGF-A/ERK Signaling

Abstract: Conclusion: Radioactive ¹²⁵I seeds inhibit nasopharyngeal carcinoma cell growth and tumor progression more effectively than X-ray irradiation by inducing DNA damage and apoptosis, as well as suppressing VEGF-A/ERK signaling-mediated cell migration. These findings suggest that ¹²⁵I seed implantation holds potential clinical value, particularly for locally recurrent nasopharyngeal carcinoma.

Authors: Huang Zuoping, et al.

Source: PLoS One, 8(9), e74038

Circulating tumor cells and clusters as liquid biomarkers for the diagnosis and prognosis of neuroblastoma

Abstract: To evaluate circulating tumor cells as diagnostic and prognostic biomarkers for neuroblastoma. Conclusion: CTCs and cell clusters are sensitive non-invasive biomarkers, with cell clusters showing a strong correlation with bone marrow metastasis.

Authors: Dai Wenyan, et al.

Source: BMC Cancer, Volume 25, Article number 1118, (2025)

The Complete Recanalization of PICC-related Venous Thrombosis in Cancer Patients: A Series of Case Reports

Abstract: Panax notoginseng saponins (PNS) effectively dissolve PICC-related venous thrombosis in cancer patients, achieving complete vascular recanalization without the bleeding risks associated with traditional thrombolytic agents, providing a feasible and effective treatment option for cancer patients with PICC-related venous thrombosis.

Authors: Zuoping Huang, Xingjing Liu, Binxin Zou, Ligen Wang, and Tao Zhou

Source: Experimental and Therapeutic Medicine, 6(2), 411-412.

Next-generation immunotherapy in relapsed/refractory multiple myeloma: Strategies to achieve sustained MRD negativity

Abstract: A critical review of immunotherapy strategies for relapsed/refractory multiple myeloma. Conclusion: Novel agents and immunotherapies offer new hope for achieving sustained MRD negativity and improving outcomes.

Authors: Ling Zhu, Muhammad Asad Nawaz, Yao Zuo, Piaoqi Zeng

Source: Critical Reviews in Oncology / Hematology, 214 (2025), 104913

Start Your Global Expert ConsultationLet Science Provide the Answer for Life

Free Consultation

Patient's Name

Cancer type

Phone number/Whatsapp

Age

Medical reports

YesNo

Upload report (optional)

Kuala LumpurPenang

Research-Driven · Precision & Minimally Invasive

Supported by effective regimens validated in SCI-indexed publications, we have introduced internationally recognized cutting-edge oncology technologies. These advanced approaches not only eliminate lesions with precision but also maximally preserve the patient’s overall well-being.

Minimally Invasive Interventional Therapy

Drug concentration 2–92 times higher than systemic chemotherapy

Local administration, bypassing systemic circulation

Radioactive Seed Implantation Therapy

Continuous internal irradiation for up to 180 days

Low radiation dose with minimal damage to normal tissues

Cryoablation and Combined knife

Alternating temperatures of –196 °C and 80 °C to inactivate tumors

Well-defined and controllable ablation margin, triggering in situ antitumor immune response

Microwave Ablation Therapy

10-minute high-temperature ablation to inactivate tumors

High thermal efficiency with complete tumor necrosis

Interventional Therapy：High-concentration drugs directly reach the tumor and kill it accurately

Compared to traditional intravenous chemotherapy, interventional therapy offers advantages such as being minimally invasive, achieving drug concentrations tens of times higher, and having fewer side effects. By directly targeting tumor tissue, interventional therapy effectively destroys cancer cells, providing better outcomes and improved quality of life for patients.

Radioactive Seeds Implantation: precise irradiation at close range, killing tumors with high doses

Radioactive Seeds Implantation breaks through the shortcomings of traditional surgery and external beam radiotherapy. It provides local high-dose precise irradiation and continues to emit gamma rays for many days to kill tumor cells. Patients have a high quality of life and remarkable curative effects!

Combined Knife: A new anti-cancer technology which redefine cold and heat ablation

Combined Knife is applicable for more than 80% of solid tumors, such as liver cancer, lung cancer, pancreatic cancer, thyroid cancer, prostate cancer and other primary and metastatic solid tumor of various organs.