Title:【Innovative Minimally Invasive Technology For Cancer Treatment Sharing Session】 Invite you to join us!    Time:From April 19th to 22th    Free online consultation appointment!
Title:【Innovative Minimally Invasive Technology For Cancer Treatment Sharing Session】 Invite you to join us!      Time:From April 19th to 22th      Free online consultation appointment!
Tongue cancer

What Is Tongue Cancer?

Tongue cancer is the most common oral cancer, which mostly occurs in the margin of tongue, and other regions such as tip, dorsum and root of tongue. Tongue cancer is often manifested as ulcerated or infiltrative type.

According to statistics, the incidence rate of tongue cancer accounts for 0.8 % to 1.5% of systemic malignant tumors, 5% ~7.8 % of malignant tumors in head and neck, and 32.3% ~ 50.6 % of oral cancer. The incidence rate of tongue cancer is higher in men than women, and average age of incidence is about 60 years old.

So can middle and late-stage tongue cancer be cured? Minimally invasive techniques with little side effects and trauma can help bladder cancer patients avoid surgical resection, avoid suffering from traditional radiotherapy, and effectively prolong the survival period.

For more knowledge about cancer, please click online doctors for consultation.

Tongue cancer Traditional Treatment Methods

  • Surgical treatmentSurgery to remove cancerous tissue and clean cervical lymph nodes that may have metastasis.

  • Radiation TherapyRadiation therapy for follicular adenocarcinoma.

  • chemotherapyOften used as palliative therapy for inoperable or distantly metastatic advanced cancer.

  • Chinese treatmentTraditional Chinese medicine therapy can inhibit the development of cancer, improve the immune function of patients with thyroid cancer, and reduce the toxic and side effects of radiotherapy and chemotherapy.
Tongue cancer Treatment Technology
Combined Knife
Combined Knife, it’s not actual surgical knife, but a composite cryogenic freezing surgical system, which conduct cold and heat a
Interventional Therapy
Interventional Therapy
Interventional therapy is a mini-invasive therapy performed under the guidance of medical imaging equipments. With a 1-2 millimeter
Nanoknife Technology
Nanoknife is a brand-new cutting-edge ablation technology for tumor treatment. It breaks the membrane of tumor cells with high volt
Particle Knife
Particle knife (also called 125I Seed Implants) is applied to a variety of primary and metastatic tumors nowadays. 125I seeds are s
Cryotherapy, also named cryosurgery therapy or cryoablation, is a medical technique both ancient and modern.
Drug-eluting bead transcatheter arterial chemoembolization
Drug-eluting beads transcatheter arterial chemoembolization (DEB-TACE) is an interventional therapy used in tumor treatment. It is
Radiofrequency Ablation
Radiofrequency ablation, sometimes referred to as RFA, is a minimally invasive treatment for cancer. It is an image-guided techniqu
Tongue cancer Patients' Story
They come from different countries around the world, but they have experienced the same experience and endured the pain that cancer has brought to them. However, now, with the effective treatment and meticulous care of St. Stamford Modern Cancer Hospital Guangzhou, they have rekindled their confidence in life and become anti-cancer fighters. Here, they share their anti-cancer experience, love and warmth with everyone.
Interventional Therapy Gives a New Life to a Thai with Lung Cancer Lung cancer
Ms. Manussawan
ThailandSurvive for more than 3 years

“Hearing the news of China’s reopening, I immediately made up my mind to come back for a follow-u...

Interventional Minimally Invasive Therapy: Restoring Hope to Life for Stage IV Lung Cancer PatientsLung Cancer
IndonesiaMore than 5 years

"hello, dear Friends, we don't need to worry and be afraid when we come to Guangzhou, China for treat...

Patient with 5-year Liver Cancer Felt The Beauty of Life  Again Given by St.Stamford Modern Cancer Hospital GuangzhouLiver cancer
Mr. Xie
MalaysiaSurvive for more than 5 years

"I am the first Southeast Asian who came to the hospital for treatment after the Covid-19 pandemic" s...

Tumor still remains inside the 81-year-old body after 5 sessions of chemotherapy, but killed by Combined Knife treatment lung cancer
Mr. Sun
ChinaSurvive for more than 2 years

It’s approaching the time for ward round of doctors in the morning, however, Mr. Sun from Oncology...

Combined Knife: A Raised Sword Accurately Inactivates the 10CM Tumorspindle cell sarcoma
Ms. Li
ChinaSurvive for more than 5 years

On March 7, led by Dai Wenyan, the director of the 1st Oncology Department in our hospital, with the ...

With Minimally Invasive Treatment,a 64-year-old Rectal Cancer Patient Was Reborn!Colorectal cancer
IndonesiaSurvive for more than 6 years

The 64 years old man, he wears a black bowler hat, hale and hearty, and his smiling eyes are glitteri...

Cancer Patients Shared Their Experience: Comprehensive Minimally Invasive Therapy Let Us Move Forward on the Journey of Fighting Cancerstomach cancer
IndonesiaSurvive for more than 8 years

According to the statistics of the Health Department of Malaysia in 2018, the incidence rate of stoma...

Treatment stories of female cancer patients: minimally invasive therapies freed us from the sufferings caused by traditional therapiesbreast cancer
Ms. Chen
MalaysiaSurvive for more than 9 years

According to the statistics of the WHO, the incidence rate of breast cancer in Malaysia in 2020 was 3...

Minimally Invasive Therapy Helps New Mother Win the Battle against Breast Cancer*Breast Cancer
IndonesiaSurvive for more than 5 years

SAIDAH, comes from Indonesia, was diagnosed with stage IIIB breast cancer. In local hospital, she got...

Minimally Invasive Therapy Benefit A Malaysian Gallbladder Cancer Patient in His Seventies*Gallbladder Cancer
MalaysiaSurvive for more than 5 years

ONG LEE SING, 72 years comes from Malaysia. He was diagnosed with well-differentiated adenocarcinoma ...

After nano-knife & interventional therapy, Vietnamese Buddhist master breaks the curse of "only 3 months survival of liver cancer" Liver Cancer
VietnamSurvive for nearly 5 years

On November 15, 2023, during the event "The Come-home Gala of Anti-cancer Stars Belt and Road Holisti...

70-year-old Man Fight Cancer with Minimally Invasive Therapy*non-Hodgkin's lymphoma
IndonesiaSurvive for more than 4 years

HENKY TJANDRA, comes from Indonesia, was diagnosed with non-Hodgkin's lymphoma in May, 2019. In St. S...

Minimally Invasive Therapy Creates 12-year Breast Cancer Survivor*Breast Cancer
IndonesiaSurvive for more than 16 years

CARINA, diagnosed with breast cancer, was treated with comprehensive therapy in local hospital. After...

Minimally Invasive Therapy: A Better Choice for Stage IV Ovarian Cancer Patient*Ovarian Cancer
PhilippinesSurvive for more than 5 years

ERLINDA FRANCISCO, 73 years old, comes from Cebu, the Philippines. In March, 2019, she was diagnosed ...

Vietnamese esophageal cancer patient: I have confidence in minimally invasive treatment*Esophageal Cancer
VietnamSurvive for more than 5 years

Vietnamese patient DAM VAN HOE was diagnosed with esophageal cancer in November 2018 with liver, medi...

Interventional Therapy-An Ideal Option for Advanced Lymphoma Patient*Lymphoma
IndonesiaSurvive for more than 5 years

MICHAEL SANJAYA IRAWAN, 22 years old, comes from Surabaya, Indonesia. In 2018, he was diagnosed with ...

Surgery is not the Only Resolution for Endometrial Cancer*Endometrial Cancer
IndonesiaSurvive for more than 5 years

YATI, comes from Indonesia, was diagnosed with endometrial cancer. In 2018, she arrived at St. Stamfo...

Minimally Invasive Therapy Offers Better Option for Lung Cancer Patient*Lung Cancer
Nguyen Van Chuyen
VietnamSurvive for more than 5 years

Nguyen Van Chuyen, 55 years old, comes from Vietnam. He is a cancer patient suffering stage IIIA lung...

With 4 months minimally invasive therapy, stage 3B thymic carcinoma reduced to 1cm*thymus cancer
IndonesiaSurvive for more than 5 years

fter confirmation in St. Stamford Modern Cancer Hospital Guangzhou, TARUMA TRIBUDIMAN was diagnosed a...

Thank St. Stamford Modern Cancer Hospital Guangzhou for being there in the toughest time of my life*Lung Cancer
Thi Hue Nguyen
VietnamSurvive for more than 5 years

After particle implantation and interventional therapy in St. Stamford Modern Cancer Hospital Guangzh...

Song Shijun
Song Shijun
Chief Expert of Oncology Department | Chief physician

Specialty:Song Shijun, professor, chief physician, CPC member, has been engaged in clinical...


Liu Yuansheng
Liu Yuansheng
Minimally Invasive Dean, Integrative Medicine Chief Expert | Deputy Chief Physician

Specialty:He has been engaged in comprehensive minimally invasive Interventional Therapy of...


Peng Xiaochi
Peng Xiaochi
Director of Oncology Department | Chief Physician

Specialty:Peng Xiaochi, M.D., Ph.D. graduate in Canada, is a member of the Chinese Medica...


Dai Wenyan
Dai Wenyan
Director of Oncology Department of Oncology, Director of Breast Cancer Center | Associate Chief Physician

Specialty:She specializes in various minimally invasive treatments for tumors, especially c...


Ma Xiaoying
Ma Xiaoying
Director of Oncology Department | Associate Chief Physician

Specialty: Ma Xiaoying, more than 20 years experience of clinical work in oncology, and i...


 Lin Jing
Lin Jing
Deputy Director, International Oncology Ward |  Attending Physician

Specialty:Dr. Lin Jing has been engaged in clinical work in oncology for nearly 20 years an...


Wu Qingkai
Wu Qingkai
Chief doctor | Attending Doctor

Specialty:With cancer clinical experience for more than 30 years, Dr. Wu Qingkai has rich m...


Zhen Yanli
Zhen Yanli
Director of Radiology Department | Associate Chief Physician

Specialty:Dr. Zhen Yanli has been engaging in the work of surgical treatment, medical imagi...


Yin Pingshan
Yin Pingshan
Distinguished expert of TCM Oncology | Chief Physician

Specialty:| Introduction Engaged in clinical work in Traditional Chinese Medicine Internal ...


Zhao Yifan
Zhao Yifan
Oncology Resident | Physician-in-Charge

Specialty:Skilled in the diagnosis and treatment of a variety of common solid tumors, speci...


Patient's Name *
Cancer type *
Phone number/Whatsapp *
Medical reports*
Tongue Cancer Symptoms

Tongue cancer is the most common oral cancer, and it accounts for 32%-39% of all oral cancers. As the incidence of tongue cancer rises gradually, to know and understand its causes and symptoms will help you detect and treat it early.

Causes of Tongue Cancer

1. Physical factors: chronic ulcers caused by continual friction between local lesions (residual root, residual crown and sharp dental ridge) and the margin of tongue may further develop into tongue cancer. Unhealthy oral hygiene can lead to choric inflammation. Plus mechanical injuries, it can be another co-carcinogenic factor. X-ray is also one of the physical factors; there are many cases caused by radiotherapy clinically.

2. Chemical factors: Addiction to tobacco and alcohol are found to be related to the occurrence of tongue cancer. The nicotine in tobacco may cause cancer. Alcohol does not cause cancer, but ethanol in it can be solvent of cancerogenic substances and carry them into the mucous membrane of tongue.

3. Biological carcinogens: Previous studies have showed that some papilloma viruses are related to the cause of tongue cancer.

4. Others: low immunity, nutrition metabolism diseases, etc.

5. Precancerous lesions: clinically some tongue cancers have oblivious precancerous pathological changes or lesions.

For more knowledge about cancer, please click online doctors for consultation. 

Signs and Symptoms of Early-stage Tongue Cancer

Most tongue cancers develop on normal mucous membrane of tongue, which show as primary lesions. Only a few of them are developed from precancerous lesions. Most tongue cancers have no obvious early symptoms. When patients go to see a doctor due to tongue pain, usually the tumors have already exceeded 1-2 cm. Early-stage tongue cancers may be manifested as ulcerated, exophytic or infiltrative type. Exophytic tongue cancers are developed from canceration of papilloma, like cauliflowers. The most common clinical presentations of tongue cancer are ulcerated or infiltrative type often with spontaneous pain or tenderness, and some people even feel ear pain. Those lesions may accompany with infection, bleeding and stink. When cancer invades the muscles of tongue, it will cause rigid tongue, difficulty in swallowing, speech problems and increased discharge of saliva.

Signs and Symptoms of Advanced-stage Tongue Cancer

In advanced tongue cancer, tumor will invades organs on the other side of the cancer or mouth floor or even spread to lingual periosteum, osteone and bones of mandible. The tongue is rich of blood vessels and lymph nodes, so frequent compression of the muscle of tongue is especially easy to cause cancer cells to spread to lymph nodes of the neck. Most metastases are found in superior deep cervical lymphatic nodes. If the primary lesion spread to lymph nodes on the other side of the neck, then the metastases will be doubled. In advanced stage, tongue cancer may spread to lungs or other distant parts of the body.

Experts from St. Stamford Modern Cancer Hospital Guangzhou remind you that once any abnormity is found, please go for treatment as soon as possible.

For more knowledge about cancer, please click online doctors for consultation. 

Tongue Cancer Diagnosis

Tongue cancer is a malignant tumor occurring in the tongue, divided into oral tongue carcinoma (2/3 anterior part of tongue) and tongue-base carcinoma (1/3 rear part of tongue). oral tongue carcinoma belongs to oral cancer, while tongue-base carcinoma is a kind of oropharyngeal cancer. Tongue cancer diagnosis is based on following examinations.

Clinical examination for tongue cancer

Cervical region, local and whole body condition should be paid attention when doing tongue cancer examination.

1. Local lesions of tumor: local lump or ulcer is the main clinical symptom of tongue cancer. Most mucosal faces of tumors are found ulcerative, necrotic, pseudomembrane or inclined to bleed. The hardened and unmovable lump would bleed when it is touched. Odors may be smelled because of tumor ulcer in individual cases. some patients may have difficulties in moving their tongues.

2. Enlargement of submandibular and cervical lymph nodes: when developing to a certain extent, tongue cancer may cause enlargement of submandibular and cervical lymph nodes by lymphatic metastasis. Those enlarged and hardened lymph nodes have little movability and may integrate together. In some serious cases, lymph nodes ulcerate and infection occurs.

Imageological examination for tongue cancer

Tongue cancer mainly occurs in the margin of 2/3 anterior part of tongue, followed by other regions such as tip, dorsum and root of tongue. Imageological examination is used to show the lesion extent and lymphatic metastasis condition. MRI is the first choice and sagittal check is the best compared with coronary and axial checks, which can differentiate normal membrane, submucosa, muscular layer and intermuscular space. Lesions can be shown clearly by fat suppressing T2WI and enhanced fat suppressing T1WI. CT scans is better than MRI in showing such bone destruction as lower jawbone, hyoid bone destruction. Enhanced multilayer spiral CT scans can also show lesions in sagittal view clearly.

Imaging manifestations of tongue cancer: 

1. oral and oropharyngeal cavities become smaller and degenerate, with normal structure of fat line shadow between tongue muscle shifting, breaking off or disappearing.

2. Lump in tongue: CT scans show equal or low density, and MRI shows long T1 and T2 signals. There is even enhancement and necrotic cystic lesion is irregularly ring-like enhanced. 

3. Advanced tongue cancer will spread around: it may affect palatoglossal arch and tonsils, and advanced tongue cancer may spread to mouth floor, jaw bone and hyoid bone. 

4. Enlarged lymph nodes: tumor in the front of tongue mainly spread to deep upper and middle groups of lymph nodes in jaw and neck; tumor in tongue tip may spread to chin or middle groups of deep cervical lymph nodes; tumor in the root of tongue may spread to not only deep jaw and cervical lymph nodes groups, but also lymph nodes located in rear belemnoid part and pharynx; tumor in the dorsum or cross the tongue centerline may spread to contralateral cervical lymph nodes. 

5. Distant metastasis: tongue cancer is easy to metastasize with high metastasis rate, and it mainly metastasizes to lung.

Laboratory examination for tongue cancer

Detection of the expression levels of such tumor markers as p53, c-myc, telomerase and the detection of R-70 are conducive to early diagnosis of tongue cancer.

The more early tongue cancer is detected, the better curative effects can be achieved. If there are any oral or pharyngeal cavities discomfort, go to normal hospital for examination and treatment as soon as possible.

For more knowledge about cancer, please click online doctors for consultation. 

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